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Socio-economic outcomes among long-term childhood acute lymphoblastic leukaemia survivors enrolled between 1971 and 1998 in EORTC CLG studies: Results of the 58LAE study
[journal article]
Abstract Objective: The objective of this study is to evaluate the socio-economic outcomes of survivors of childhood acute lymphoblastic leukaemia (ALL). Methods: Childhood ALL adult survivors, enrolled in EORTC trials between 1971 and 1998 in France and Belgium, were invited to fill out a questionnaire with... view more
Objective: The objective of this study is to evaluate the socio-economic outcomes of survivors of childhood acute lymphoblastic leukaemia (ALL). Methods: Childhood ALL adult survivors, enrolled in EORTC trials between 1971 and 1998 in France and Belgium, were invited to fill out a questionnaire with information about their socio-economic situation (living with a partner, having a university degree, having a job, working part time and history of having a paid job). The outcomes were compared with two matched control populations. Results: Among 1418 eligible patients, 507 (35.8%) participated, including 39 (8%) and 61 (12%) patients who received a haematopoietic stem cell transplantation (HSCT) and a cranial radiotherapy (CRT), respectively. The median time to follow-up was 20 years, and median age was 25 years. Survivors showed a socio-economic level at least as good as controls. HCST and CRT were associated with a higher probability of not obtaining a bachelor degree (respectively OR=3.49, 95% CI: 1.46-8.35 and OR=2.31, 95% CI: 1.04-5.15), HSCT was associated with unemployment (OR=2.89, 95% CI: 1.09-7.65) and having a relapse was associated with a higher probability of not having a partner (OR=1.88, 95% CI: 1.01-3.51) adjusting for confounders. Conclusion: Childhood ALL survivors showed a high level of socio-economic participation. HCST and CRT were associated with poorer functioning.... view less
Keywords
cancer; twentieth century; child; socioeconomic factors; illness
Classification
Medical Sociology
Free Keywords
EU-LFS
Document language
English
Publication Year
2022
Page/Pages
p. 1-11
Journal
European Journal of Cancer Care, 31 (2022) 6
DOI
https://doi.org/10.1111/ecc.13755
ISSN
1365-2354
Status
Published Version; peer reviewed