Socio-economic outcomes among long-term childhood acute lymphoblastic leukaemia survivors enrolled between 1971 and 1998 in EORTC CLG studies: Results of the 58LAE study

Barbati, Melissa; Kicinski, Michal; Suciu, Stefan; Mazingue, Françoise; Vandecruys, Els; Plat, Geneviève; Uyttebroeck, Anne; Paillard, Catherine; Dresse, Marie-Françoise; Simon, Pauline; Pluchart, Claire; Minckes, Odile; Ferster, Alina; Freycon, Claire; Millot, Frederic; Van Der Werff ten Bosch, Jutte; Chantrain, Christophe; Paulus, Robert; Schaetzen, Gaetan de; Rossi, Giovanna; Rohrlich, Pierre; Benoit, Yves; Piette, Caroline

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%T Socio-economic outcomes among long-term childhood acute lymphoblastic leukaemia survivors enrolled between 1971 and 1998 in EORTC CLG studies: Results of the 58LAE study
%A Barbati, Melissa
%A Kicinski, Michal
%A Suciu, Stefan
%A Mazingue, Françoise
%A Vandecruys, Els
%A Plat, Geneviève
%A Uyttebroeck, Anne
%A Paillard, Catherine
%A Dresse, Marie-Françoise
%A Simon, Pauline
%A Pluchart, Claire
%A Minckes, Odile
%A Ferster, Alina
%A Freycon, Claire
%A Millot, Frederic
%A Van Der Werff ten Bosch, Jutte
%A Chantrain, Christophe
%A Paulus, Robert
%A Schaetzen, Gaetan de
%A Rossi, Giovanna
%A Rohrlich, Pierre
%A Benoit, Yves
%A Piette, Caroline
%J European Journal of Cancer Care
%N 6
%P 1-11
%V 31
%D 2022
%K EU-LFS
%@ 1365-2354
%~ FDB
%> https://nbn-resolving.org/urn:nbn:de:0168-ssoar-91687-8
%X Objective: The objective of this study is to evaluate the socio-economic outcomes of survivors of childhood acute lymphoblastic leukaemia (ALL). Methods: Childhood ALL adult survivors, enrolled in EORTC trials between 1971 and 1998 in France and Belgium, were invited to fill out a questionnaire with information about their socio-economic situation (living with a partner, having a university degree, having a job, working part time and history of having a paid job). The outcomes were compared with two matched control populations. Results: Among 1418 eligible patients, 507 (35.8%) participated, including 39 (8%) and 61 (12%) patients who received a haematopoietic stem cell transplantation (HSCT) and a cranial radiotherapy (CRT), respectively. The median time to follow-up was 20 years, and median age was 25 years. Survivors showed a socio-economic level at least as good as controls. HCST and CRT were associated with a higher probability of not obtaining a bachelor degree (respectively OR=3.49, 95% CI: 1.46-8.35 and OR=2.31, 95% CI: 1.04-5.15), HSCT was associated with unemployment (OR=2.89, 95% CI: 1.09-7.65) and having a relapse was associated with a higher probability of not having a partner (OR=1.88, 95% CI: 1.01-3.51) adjusting for confounders. Conclusion: Childhood ALL survivors showed a high level of socio-economic participation. HCST and CRT were associated with poorer functioning.
%C GBR
%G en
%9 Zeitschriftenartikel
%W GESIS - http://www.gesis.org
%~ SSOAR - http://www.ssoar.info