A Systematic Review of Global Research on Post Infectious Bronchiolitis Obliterans in Children

Abstract

The article aims to analyse the diagnosis of PIBO, inform readers about prediction models, and explore current therapeutic trends.The Systematic Review was conducted as per PRISMA reporting guidelines. The search was done from PUBMED, Cochrane Library, Embase, and Google Scholar for relevant recent studies till September 2023. The study was selected for those satisfying the following criteria: 1) Studies include only children with Post- Infectious Bronchiolitis Obliterans; 2) Original articles with cross-sectional, case-control, and RCT were included. The data collected includes the type of study, author, publication year, study period, study design, study country, number of participants, diagnostic criteria of Post-Infectious Bronchiolitis Obliterans, respiratory pathogens, risk factors, and current therapy trends. The first part of the study involves making the entity of Post-Infectious Bronchiolitis Obliterans well understood through the various primary studies. The second part is about medical treatment attempted successfully by multiple professionals and their studies. Studies including Haematopoietic Stem Cell Transplantation, Lung Transplantation, and chronic lung disease were excluded.With this information, an attempt has been made to simplify the identification of PIBO, avoid misdiagnosis, and shed some light on the various Prediction models for PIBO and the therapies tried with some success.